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Defensin alpha 1 plays a crucial role in the carcinogenesis of ductal adenocarcinoma of the pancreas

✍ Scribed by Pausch, T.; Schneider, S.; Felix, K.; Schneider, K.; Giese, N.; Büchler, M.W.; Werner, J.; Hartwig, W.

Book ID
122786283
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
43 KB
Volume
12
Category
Article
ISSN
1424-3903

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## Abstract Genetic and epigenetic alterations during development of pancreatic ductal adenocarcinomas (PDACs) are well known. This study investigates genetic and epigenetic data together with tumor biology to find specific alterations responsible for metastasis formation. Using 16 human PDAC cell