Defects in the Leukocyte Adhesion Cascade
β Scribed by Amos Etzioni
- Book ID
- 107568429
- Publisher
- Humana Press Inc
- Year
- 2009
- Tongue
- English
- Weight
- 177 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1080-0549
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π SIMILAR VOLUMES
## Heterogeneity in the molecular defect leading to the leukocyte adhesion deficiency* Leukocyte adhesion deficiency (LAD) is a recessive autosomal disease characterized by life-threatening recurrent bacterial infections, by defective functions of leukocytes and by deficient membrane expression of
Communicated by Charles J. Epstein Leukocyte adhesion deficiency (LAD) is an inherited immunodeficiency disorder caused by CD 18 subunit abnormality dependent defective expression of pz integrins on the surface of leukocytes. On analysis of the CD18 molecular defect in a female Japanese patient with