Implications of low COX-2 expression in
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William E. Karnes Jr.
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Article
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2000
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John Wiley and Sons
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English
β 69 KB
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Most colorectal adenomas and carcinomas arise in the setting of chromosomal instability and progressive loss of heterozygosity. Approximately 15-20% of colorectal neoplasms arise through a distinct genetic pathway characterized by microsatellite instability (MSI) and frequent loss of expression of o