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Defective lymphokine production by most CD8+ and CD4+ tumor-specific T cell clones derived from human melanoma-infiltrating lymphocytes in response to autologous tumor cells in vitro

✍ Scribed by Yannick Guilloux; Christophe Viret; Nadine Gervois; Eric Le Dréan; Marie-Christine Pandolfino; Elisabeth Diez; Francine Jotereau

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
789 KB
Volume
24
Category
Article
ISSN
0014-2980

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✍ Franck Housseau; Daniel A. Langer; Samuel D. Oberholtzer; Anitha Moorthy; Hyam I 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 150 KB 👁 2 views

## Abstract To identify tumor‐associated antigens as putative targets for developing immunotherapies against prostate cancer, we investigated the ability of T cells derived from the peripheral blood lymphocytes of prostate cancer patients to recognize autologous tumor cells. The technical challenge