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Deep vein thrombosis detection by 99mTc-plasmin test and phlebography

✍ Scribed by S. E. Husted; Dr H. Krámmer Nielsen; L. Krusell; H. Fasting; B. Ostergaard Nielsen; J. Bruun Pedersen; E. Dalgaard; H. Hvid Hansen

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
252 KB
Volume
71
Category
Article
ISSN
0007-1323

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✦ Synopsis

Deep vein thrombosis detection by 99mTc-plasmin test and phlebography

During a 2-year period the diagnostic value of 99mTc-labelled-plasmin test was evaluated in 63 patients admitted with clinical signs of deep vein thrombosis (D V7'). In comparison with a conventional phlebography the diagnostic sensitivity and specifcity of the plasmin test was 0.97 and 0.55, respectively. The predictive value in positive cases was 0.79 and in negative 0.92. The sensitivity was highest for thrombosis in the calf and popliteal regions, while the specifcity was higher for thrombosis in the fimoral veins. It is concluded that the 99m Tc-labelled-plasmin test is suitable for D VT-screening in groups of high-risk patients and is simple and rapid. In positive cases the DVT diagnosis must be verged by p hlebograp h y.

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