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Deep brain stimulation for the treatment of atypical parkinsonism

✍ Scribed by Ludy C. Shih; Daniel Tarsy

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
74 KB
Volume
22
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

Deep brain stimulation (DBS) has gained widespread acceptance for improving motor function and disability in Parkinson's disease (PD). Patients with features suggestive of atypical parkinsonism (AP) usually have a poorer and less sustained response to levodopa and a poorer prognosis overall when compared with patients with PD. However, experience in the use of DBS with this group of patients is limited and evidence is lacking with regards to its efficacy and adverse effects. We review in detail the experience of DBS surgery in patients with several forms of AP including multiple system atrophy. On the basis of the limited available data reviewed here, DBS for patients with AP is not recommended. Β© 2007 Movement Disorder Society

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