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Deep brain stimulation as a mode of treatment of early onset pantothenate kinase-associated neurodegeneration

✍ Scribed by Mohamad A. Mikati; Amin Yehya; Houssein Darwish; Pascale Karam; Youssef Comair


Book ID
113590318
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
184 KB
Volume
13
Category
Article
ISSN
1090-3798

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## Abstract Pantothenate kinase‐associated neurodegeneration (PKAN) is a rare autosomal recessive disorder with onset in childhood and rapid progression. There is no causative and insufficient symptomatic drug therapy. Deep brain stimulation (DBS) of the internal pallidum (GPi) has been reported to