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Dedifferentiation of human articular chondrocytes is associated with alterations in expression patterns of GDF-5 and its receptors

✍ Scribed by Werner Schlegel; Christian Albrecht; Peter Eckl; Harald Freudenthaler; Angelika Berger; Vilmos Vécsei; Stefan Marlovits

Book ID
114778713
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2009
Tongue
English
Weight
770 KB
Volume
13
Category
Article
ISSN
1582-1838

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## Abstract Interleukin (IL)‐4, which exhibits potent anti‐inflammatory activities, is of potential therapeutic value in destructive arthropathies. To further define the response of human joint cells to IL‐4, we analyzed the ability of this cytokine to modulate the effects of IL‐1β and growth facto