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DEDC, a new flavonoid induces apoptosis via a ROS-dependent mechanism in human neuroblastoma SH-SY5Y cells

✍ Scribed by Huibin Liu; Chunyang Jiang; Chaomei Xiong; Jinlan Ruan


Book ID
116920538
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
840 KB
Volume
26
Category
Article
ISSN
0887-2333

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## Abstract Neuroblastoma is the most common extracranial solid tumor in children causing death at pre‐school age, as no cure has yet been developed. We investigated the proteolytic mechanisms for apoptosis in human malignant (N‐type) neuroblastoma SH‐SY5Y cells following exposure to flavonoids suc