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Decrement of muscarinic receptor-stimulated low-KMGTPase in striatum and hippocampus from the aged rat

✍ Scribed by K. Yamagami; J.A. Joseph; G.S. Roth

Book ID
115802869
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
543 KB
Volume
576
Category
Article
ISSN
0006-8993

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## Abstract Hippocampal receptor‐mediated phosphoinositide (PI) turnover is severely blunted in aged rats that demonstrate cognitive deficits in the Morris water maze. To further examine the anatomical localization of this deficit, we examined the topography of muscarinic receptor‐mediated PI turno