Decreasing glycolysis increases sensitivity to mitochondrial inhibition in primary cultures of renal proximal tubule cells
โ Scribed by Richard D. Griner; Rick G. Schnellmann
- Book ID
- 112801884
- Publisher
- Society for In Vitro Biology
- Year
- 1994
- Tongue
- English
- Weight
- 509 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1475-2689
No coin nor oath required. For personal study only.
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Abnormal glucose handling in the proximal tubule may play an important role in the development of diabetic nephropathy. Thus, the present study was designed to examine the effect of high glucose on alpha-methyl-D-glucopyranoside (alpha-MG) uptake and its signaling pathways in the primary cultured ra
## Abstract Oxidative stress, the result of cellular production of reactive oxygen species (ROS), has been implicated in causing many renal diseases. Adenosine triphosphate (ATP) is an important extracellular signal in the regulation of many intracellular processes in normal tubular cells as well a