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Decreased somatostatin-like immunoreactivity in cerebral cortex and cerebrospinal fluid in Alzheimer's disease

โœ Scribed by K.J. Reinikainen; P.J. Riekkinen; J. Jolkkonen; V.-M. Kosma; H. Soininen


Book ID
115797493
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
532 KB
Volume
402
Category
Article
ISSN
0006-8993

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A competitive enzyme-linked immunosorbent assay with high sensitivity has been developed for measuring ubiquitin reactivity of paired helical filaments (PHF). Using the assay, ubiquitin immunoreactivity was estimated in the cerebrospinal fluid (CSF) of 44 patients who had been clinically diagnosed a