## Abstract Necroptosis is programmed necrosis triggered by death receptor signaling. We investigated whether necroptosis contributes to neuronal damage and functional impairment in a model of retinal ischemia. Methods: SpragueβDawley rats were subjected to raised intraβocular pressure for 45 min a
β¦ LIBER β¦
Decreased Retinal Neuronal Cell Death in Caspase-1 Knockout Mice
β Scribed by Jun Arai; Naomichi Katai; Keisuke Kuida; Takanobu Kikuchi; Nagahisa Yoshimura
- Book ID
- 106327290
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 320 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0021-5155
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Transforming growth factor-β€1 (TGF-β€1) regulates a variety of cellular functions. In several types of cells, for example, it acts as a growth inhibitor and an inducer of apoptotic cell death. Although one of the important modulators in retinal vascular development and retinal neovascularization, the