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Decreased protein kinase C activity in hypertrophied left ventricle induced by pressure-overload hypertrophy

✍ Scribed by Xin Gu; Sanford P. Bishop; Tommy A. Brock; Clifford C. Stephan

Book ID
115985043
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
90 KB
Volume
24
Category
Article
ISSN
0022-2828

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## Abstract Recent in vitro studies suggest that adenosine monophosphate (AMP)‐activated protein kinase (AMPK) exerts inhibitory effects on cardiac hypertrophy. However, it is unclear whether long‐term activation of AMPK will affect cardiac hypertrophy in vivo. In these reports, we investigate the