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Decreased production of reactive oxygen intermediates is an early event during in vitro apoptosis of rat thymocytes

✍ Scribed by Ji-Feng Wang; Thomas R. Jerrells; John J. Spitzer

Book ID
113386776
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
830 KB
Volume
20
Category
Article
ISSN
0891-5849

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## Abstract The mechanism of induction of apoptosis by dolichyl phosphate (Dol‐P) was investigated in U937 cells. Studies using isolated mitochondria revealed that the respiratory complex II activity was almost completely inhibited by 20 µg/ml of Dol‐P but not by the same concentration of dolichol.