Decreased Plasma Brain-Derived Neurotrophic Factor Levels in Patients With Alcohol Dependence
β Scribed by Keun-Ho Joe; Yong-Ku Kim; Tae-Suk Kim; Sung-Won Roh; Sam-Wook Choi; Young-Bo Kim; Hee-Jin Lee; Dai-Jin Kim
- Book ID
- 109123889
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 188 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0145-6008
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## Abstract Alcohol dependence is often comorbid with depression. The purpose of the present study was to compare serum brainβderived neurotrophic factor (BDNF) levels between depressive patients with and without alcohol dependence. Our subjects were 16 inpatients (M/F: 13/3, age: 48βΒ±β8 years) at
Recent studies have implicated brain-derived neurotrophic factor (BDNF) in the pathophysiology of depression and in the activities of antidepressant drugs. Serum BDNF levels are lower in depressed patients and increase in response to antidepressant medications; however, no studies have examined the