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Decreased placental expression of hPGH, IGF-I and IGFBP-1 in pregnancies complicated by fetal growth restriction

✍ Scribed by Maria Koutsaki; Stavros Sifakis; Apostolos Zaravinos; Dimitrios Koutroulakis; Ourania Koukoura; Demetrios A. Spandidos


Book ID
116512396
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
285 KB
Volume
21
Category
Article
ISSN
1096-6374

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Osteogenic protein-1 (OP-1 or BMP-7) stimulates new bone formation in vivo and induces cell proliferation and differentiation of osteoblasts in vitro. Previous studies from our laboratory revealed that OP-1 led to a two-to threefold increase in steady-state insulin-like growth factor-I (IGF-I) and I