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Decreased nuclear factor-κB DNA binding activity following permanent focal cerebral ischaemia in the rat

✍ Scribed by E.A Irving; S.J Hadingham; J Roberts; M Gibbons; M Chabot-Fletcher; A Roshak; A.A Parsons


Book ID
117470866
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
459 KB
Volume
288
Category
Article
ISSN
0304-3940

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## Abstract We have previously reported that prostaglandin A~1~ (PGA~1~) reduces infarct size in rodent models of focal ischemia. This study seeks to elucidate the possible molecular mechanisms underlying PGA~1~'s neuroprotective effects against ischemic injury. Rats were subjected to permanent mid