Decreased myocardial 123 I-MIBG uptake in Parkinson's disease
β Scribed by K. Iwasa; K. Nakajima; H. Yoshikawa; A. Tada; J. Taki; M. Takamori
- Book ID
- 109336807
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 467 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0001-6314
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## Abstract Myocardial ^123^Metaiodobenzylguanidine (MIBG) enables the assessment of postganglionic sympathetic cardiac innervation. MIBG uptake is decreased in nearly all patients with Parkinson's disease (PD). Our objective was to evaluate MIBG uptake in patients with genetic PD. We investigated
Meta-123I-iodobenzylguanidine (123I-MIBG), which is an analog of norepinephrine, can be used to evaluate the integrity and function of sympathetic nerve endings in the heart. Myocardial uptake of 123I-MIBG was studied in 30 myocardial infarction patients and compared with the distribution of blood f