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Decreased insulin receptor binding in hyperthyroidism

✍ Scribed by Schernthaner, G. ;Prager, R. ;Weissel, M. ;Höfer, R.


Publisher
Springer-Verlag
Year
1984
Tongue
English
Weight
732 KB
Volume
62
Category
Article
ISSN
1432-1440

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To determine whether hyperinsulinaemia can cause insulin resistance in man and, if so, whether this occurs at a receptor or post-receptor site, nine normal volunteers were infused with insulin for 6 h at a rate (2 mU X kg-1 X min-1) which resulted in steady-state plasma insulin concentrations of 140