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Decreased expression and increased carbonylation of haptoglobin in plasma from MCI and AD subjects: Role of extracellular chaperones in Alzheimer’s disease

✍ Scribed by Cocciolo, A.; Mecocci, P.; Butterfield, D.A.; Perluigi⁎, M.

Book ID: 123263948
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 28 KB
Volume: 53
Category: Article
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2012.08.552

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## Abstract Alzheimer's disease (AD) is the most common form of dementia and is pathologically characterized by senile plaques, neurofibrillary tangles, synaptic disruption and loss, and progressive neuronal deficits. The exact mechanism(s) of AD pathogenesis largely remain unknown. With advances i