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Decreased Efficacy of GABAA-receptor Modulation by Midazolam in the Kainate Model of Temporal Lobe Epilepsy

✍ Scribed by Lia C. Liefaard; Rou-Afza F. Gunput; Meindert Danhof; Rob A. Voskuyl


Book ID
109110371
Publisher
Wiley (Blackwell Publishing)
Year
2007
Tongue
English
Weight
189 KB
Volume
48
Category
Article
ISSN
0013-9580

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Temporal lobe epilepsy (TLE) is one of the most commonly occurring and most intractable forms of seizure disorders in humans. The fundamental mechanisms underlying the pathogenesis of the disorder have, however, not yet been elucidated. El is an inbred mouse strain with genetic predisposition to epi