𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Decreased BRCA1 confers tamoxifen resistance in breast cancer cells by altering estrogen receptor–coregulator interactions

✍ Scribed by Wen, J; Li, R; Lu, Y; Shupnik, M A


Book ID
109970739
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
345 KB
Volume
28
Category
Article
ISSN
0950-9232

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## Abstract Overexpression of Her2/neu is implicated in the development of resistance to the antiestrogen tamoxifen (TAM) that exerts its inhibitory effect through interaction with estrogen receptor (ER). Whereas Her2/neu and ER are believed to be important cell survival/death factors in human brea