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Decreased activities of S-adenosylmethionine synthetase isozymes in hereditary hepatitis in Long-Evans rats

โœ Scribed by Keiko Shimizu; Makoto Abe; Sigeaki Yokoyama; Hidetoshi Takahashi; Norimasa Sawada; Michio Mori; Kinji Tsukada


Book ID
118344255
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
272 KB
Volume
46
Category
Article
ISSN
0024-3205

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The Long-Evans Cinnamon rat is a mutant strain that contracts hereditary hepatitis and, eventually, spontaneous hepatoma. Recently, abnormal copper accumulations in Long-Evans Cinnamon rat livers were shown to be genetically linked to the development of hepatitis. Because reduced glutathione and glu