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Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease

✍ Scribed by Irina N. Shalova; Katerina Cechalova; Zuzana Rehakova; Petya Dimitrova; Elisa Ognibene; Antonio Caprioli; Elena V. Schmalhausen; Vladimir I. Muronetz; Luciano Saso


Book ID
116271802
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
578 KB
Volume
1770
Category
Article
ISSN
0304-4165

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Subcellular alteration of glyceraldehyde
✍ Jennifer L. Mazzola; Michael A. Sirover πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 179 KB

## Abstract The regulation of glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) has been implicated both in age‐related neurodegenerative disease and in apoptosis. Previous in vitro studies suggest an interaction between GAPDH and the β‐amyloid precursor protein (β‐APP), a protein directly involved