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Decrease in tumor interstitial fluid pressure by pentoxifylline

✍ Scribed by Intae Lee; Thomas Demhartner; Yves Boucher; Rakesh K. Jain

Book ID
107964398
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
104 KB
Volume
24
Category
Article
ISSN
0360-3016

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## Abstract We have previously shown that osteosarcomas (OS) have states of increased interstitial fluid pressure (IFP), which correlate with increased proliferation and chemosensitivity. In this study, we hypothesized that constitutively raised IFP in OS regulates angiogenesis. Sixteen patients wi