Elevated endogenous GABA level correlate
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Zhengguang Chen; Afonso C. Silva; Jehoon Yang; Jun Shen
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Article
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2005
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John Wiley and Sons
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English
β 278 KB
## Abstract Vigabatrin and gabaculine, both highly specific inhibitors of GABA (Ξ³βaminobutyric acid) transaminase, cause significant elevation of endogenous GABA levels in brain. The time course of GABA concentration after acute GABA transaminase inhibition was measured quantitatively in the Ξ±βchlo