Decoding the Pathophysiology and the Genetics of Multiple Myeloma to Identify New Therapeutic Targets
โ Scribed by Lawasut, Panisinee; Groen, Richard W.J.; Dhimolea, Eugen; Richardson, Paul G.; Anderson, Kenneth C.; Mitsiades, Constantine S.
- Book ID
- 121722688
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 190 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0093-7754
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## Abstract The interaction between tumor cells and the local milieu where are homing has recently become the focus of extensive research in a broad range of malignancies. Among them, multiple myeloma (MM) is now recognized as a prototypical tumor model for the characterization of these interaction
note, in 19 patients, remission achieved by bortezomib-based therapy was consolidated by high-dose therapy followed by autologous stem cell transplantation. With a median follow-up time of 11 months (1 27 months), the median progression-free survival of our entire patient population is 13.8 month, w