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Deciphering the underlying genetic and epigenetic events leading to gastric carcinogenesis

✍ Scribed by Paraskevi Vogiatzi; Carla Vindigni; Franco Roviello; Alessandra Renieri; Antonio Giordano

Book ID
102312324
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
262 KB
Volume
211
Category
Article
ISSN
0021-9541

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✦ Synopsis

Abstract

Gastric cancer is a common aggressive malignancy. Although its incidence shows considerable variation among different countries, gastric cancer is still a major health problem worldwide. The causes of stomach cancer are not completely understood. What is clear is that gastric cancer is a multi‐stage process involving genetic and epigenetic factors. This review is an in‐depth study of the known genetic and epigenetic processes in the development of this tumor, and delineates possible approaches in gene and epigenetic therapy. J. Cell. Physiol. 211: 287–295, 2007. © 2007 Wiley‐Liss, Inc.

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