Decarboxylation of uroporphyrinogen I and III in 2,3,7,8-tetrachlorodibenzo-p-dioxin induced porphyria in mice
โ Scribed by L. Cantoni; D. Dal Fiume; R. Ruggieri
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 636 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0020-711X
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## Abstract The contaminant 2,3,7,8โtetrachlorodibenzoโ__p__โdioxin (TCDD) is a prototype compound of a whole class of halogenated aromatic hydrocarbons termed โdioxinlikeโ contaminants present in food, human tissue, mothers milk, and environmental samples. Among the various adverse effects caused
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## Abstract 2,3,7,8โTetrachlorodibenzoโ__p__โdioxin (TCDD) is a potent immunosuppressant in several animal species. The purpose of this study was to determine if TCDD affected the activity of adenosine deaminase (ADA), a purine metabolizing enzyme that is vital to the proper functioning of the immu