Decarbonylation of α-tertiary amino acid
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María J. Martín-López; Rosa Rodriguez; Francisco Bermejo
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Article
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1998
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Elsevier Science
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French
⚖ 821 KB
The decarbonylation of the bicyclic a-tertiary carboxamido acid 11 led to the enamide 12, easily transformed into the indolizidine alkaloid 8,8a-trans-8-hydroxy-indolizidine 14. Likewise, the same process applied to the ¢t-substituted pipecolic acid derivative 5 led to the unsaturated ester 6 which