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Debromination of 8-bromo-2′-deoxyguanosine by methylene blue and visible light

✍ Scribed by Lata Venkatarangan; Dan-Hui Yang; Gary A. Epling; Ashis K. Basu

Book ID
104260803
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
247 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

Debromination of 8-bromo-2'-deoxyguanosine was accomplished in high yield under neutral conditions in aqueous methanol by irradiating with visible light in the presence of methylene blue as a sensitizer and triethylamine as an electron donor. The method can be extended for the debromination of other bromoaromatic compounds.

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Involvement of H1 and other chromatin proteins in the formation of DNA-protein cross-links induced by visible light in the presence of methylene blue
✍ Ratna Lalwani; Subhankar Maiti; Sheela Mukherji 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 779 KB

The formation of DNA-protein cross-links (DPCs), induced by irradiation with visible light, was studied in methylene bluetreated (MB-treated) chromatin and HI-depleted chromatin. The effects of the MB concentration and radiation dose were studied using sodium dodecylsulphate-chloroform-isoamyl alcoh