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Death by a dopaminergic neurotoxin, 1-methyl-4-phenylpyridinium ion (MPP+) and protection by EGF in GH3 cells

✍ Scribed by Norihiro Yoshinaga; Toshihiko Murayama; Yasuyuki Nomura


Book ID
114003839
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
168 KB
Volume
794
Category
Article
ISSN
0006-8993

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We have studied the effect of a semichronic and acute treatment of phenobarbital on in vivo 1-methyl-4-phenylpyridinium ion- (MPP+)-induced neurotoxicity. A group of rats were intraperitoneally injected for 12 days with phenobarbital (80 mg/Kg of body weight, semichronic treatment) in order to induc