Deactivation of glass capillary columns by silylation. Part 1: Principles and basic technique

✍ Scribed by Grob, K. ;Grob, G. ;Grob, K.

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: English
• Weight: 457 KB
• Volume: 2
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/jhrc.1240020110

✦ Synopsis

A deactivation procedure is described based on a published method using hexamethyldisilazane in the gas phase. In addition to unusually high inertia and thermostability, the method produces truly neutral columns which allow simultaneous analysis of moderately strong free acids and bases. The silylated columns show their full potential only with on-column injection. Preliminary experimental directions are given; more elaborate directions will become available after extended optimization work.