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De Novo Immunosuppression With Mammalian Target of Rapamycin Inhibitors and Posttransplantation Malignancy in Focus

✍ Scribed by S. Flechner; P. Friend; J. Campistol; M. Weir; F. Diekmann; G. Russ


Book ID
116935494
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
100 KB
Volume
41
Category
Article
ISSN
0041-1345

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✍ Stephen Sonis; Nathaniel Treister; Sant Chawla; George Demetri; Frank Haluska πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 176 KB

## Abstract ## BACKGROUND: Mammalian target of rapamycin (mTOR) inhibitors may have efficacy as an intervention for advanced malignancies. Oral ulceration (OU), reported as mucositis, has been a dose‐limiting toxicity for this new class of agents. An analysis of the appearance, course, and toxicit