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dbNSFP v2.0: A Database of Human Non-synonymous SNVs and Their Functional Predictions and Annotations

โœ Scribed by Liu, Xiaoming; Jian, Xueqiu; Boerwinkle, Eric


Book ID
120619918
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
268 KB
Volume
34
Category
Article
ISSN
1059-7794

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dbNSFP: A lightweight database of human
โœ Xiaoming Liu; Xueqiu Jian; Eric Boerwinkle ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 220 KB

With the advance of sequencing technologies, whole exome sequencing has increasingly been used to identify mutations that cause human diseases, especially rare Mendelian diseases. Among the analysis steps, functional prediction (of being deleterious) plays an important role in filtering or prioritiz