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Data integration and exploration for the identification of molecular mechanisms in tumor-immune cells interaction

✍ Scribed by Bernhard Mlecnik; Fatima Sanchez-Cabo; Pornpimol Charoentong; Gabriela Bindea; Franck Pagès; Anne Berger; Jerome Galon; Zlatko Trajanoski


Book ID
115003493
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
221 KB
Volume
11
Category
Article
ISSN
1471-2164

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## Abstract Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells plays an important role in Fas‐mediated tumor killing, During tumor progression FasL‐expressing tumor cells are involved in __counterattacking__ to kill tumor‐infiltr