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Das Diazo-chinon von PQQ als mögliches Reagenz für die Kartierung von Chinoproteinen mittels Photoaffinitätsmarkierung

✍ Scribed by Pierre Martin; Tammo Winkler


Publisher
John Wiley and Sons
Year
1993
Tongue
German
Weight
228 KB
Volume
76
Category
Article
ISSN
0018-019X

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✦ Synopsis


The Diazo-quinone of P Q Q as a Possible Reagent for Mapping Quinoproteins by Photo-affinity Labeling PQQ is an organic redox cofactor found in a class of enzymes called quinoproteins. The synthesis and the photochemistry of the diazo-quinones of PQQ and PQQ-triester are described. The photogenerated Wo(ff--rearrangement products have been caught with water and methanol as model nucleophiles. The products show a strong fluorescence. The diazoquinone of PQQ may be considered as a possible reagent for mapping quinoproteins by photo-affinity labeling. ') Der Inhalt der vorliegenden Publikation war Teil einer Prasentation am '2nd International Symposium on PQQ and Quinoproteins',