Dark-rearing delays the loss of NMDA-receptor function in kitten visual cortex
β Scribed by Fox, Kevin; Daw, Nigel; Sato, Hiromichi; Czepita, Damian
- Book ID
- 109770974
- Publisher
- Nature Publishing Group
- Year
- 1991
- Tongue
- English
- Weight
- 342 KB
- Volume
- 350
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/350342a0
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Kinetics of the development of orientation tuning are inferred from quantitative analysis of extracellular recordings in the primary visual cortex of normally and dark reared kittens. 712 visual cells were classified in three functional groups: a) non-specific cells, and b) immature cells which are
The development of orientation selectivity in the primary visual cortex is described by first-order kinetics between three functional compartments chained in a catenary mode. A first model is presented, in which two unidirectional kinetics with constant exchange coefficients, symmetrical in their ef
We have investigated the postnatal development of N-methyl-D-aspartate (NMDA) receptors in kitten neocortex by measuring the density of [3H] MK801 binding sites. NMDA receptor density in area 17 markedly increases between postnatal day 7 and 35, and then remains at a high level into adulthood. Simil