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Dapper, a Dishevelled-Associated Antagonist of β-Catenin and JNK Signaling, Is Required for Notochord Formation

✍ Scribed by Benjamin N.R. Cheyette; Joshua S. Waxman; Jeffrey R. Miller; Ken-Ichi Takemaru; Laird C. Sheldahl; Natasha Khlebtsova; Eric P. Fox; Thomas Earnest; Randall T. Moon


Book ID
117795157
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
945 KB
Volume
2
Category
Article
ISSN
1534-5807

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## Abstract ## BACKGROUND: Abnormal activation of the Wnt/β‐catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene __Dkk‐3__ in these cancers and its prognostic signi