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DANGERS OF HIGH-DOSE QUININE AND OVERHYDRATION IN SEVERE MALARIA

✍ Scribed by HALL, A


Book ID
123185858
Publisher
The Lancet
Year
1985
Tongue
English
Weight
351 KB
Volume
325
Category
Article
ISSN
0140-6736

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Pharmacokinetics of quinine and 3-hydrox
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The plasma concentrations of quinine and its main metabolite, 3-hydroxyquinine (30HQn), were measured in 5 adult Thai patients with severe Plasmodium falciparum malaria and acute renal failure. Two patients required peritoneal dialysis but all survived. During acute renal failure plasma concentratio