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Danazol therapy in cyclic acquired amegakaryocytic thrombocytopenic purpura: A case report

✍ Scribed by Kashyap, Rajesh; Choudhry, V.P.; Pati, H.P.

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
139 KB
Volume
60
Category
Article
ISSN
0361-8609

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✦ Synopsis

Cyclic acquired amegakaryocytic thrombocytopenic purpura (AATP) is a rare disorder characterized by periodic fluctuations in the platelet counts due to a defect in the platelet production. We describe a 42-year-old female with cyclic AATP, in whom the cyclic fluctuations in the platelet counts ceased with danazol therapy. The pathogenesis of the disease and the possible mechanisms of danazol action have been reviewed. Am.

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