Danazol induced hypercalcemia in breast cancer
โ Scribed by Silvana Martino
- Book ID
- 105315601
- Publisher
- Springer US
- Year
- 1984
- Tongue
- English
- Weight
- 130 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0167-6806
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๐ SIMILAR VOLUMES
Hypercalcemia is relatively frequent in malignancy with or without osteolytic bone metastases. It is thought that neoplastic cells may secrete substances which not only stimulate osteoclastic activity but are also capable of modifying the absorption, excretion, and resorption of calcium and phosphat
Pre-menopausal (14) and post-menopausal (55) patients with advanced breast cancer were treated with danazol (Danol) for periods ranging between 3 days and 30 months. Of these, 10 patients (14.9%) responded to treatment for 3-19 months (mean 10 months); a further six patients (9%) showed stabilisatio