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Damage effect of chronic intoxication by CCl4 on structural organization of liver microsomes and cytochromes (b)5 and P-450

✍ Scribed by I.B. Tsyrlov; V.V. Lyachovich

Book ID
115771464
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
255 KB
Volume
21
Category
Article
ISSN
0006-2952

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✍ MartΓ­n MartΓ­nez; Marisabel Mourelle; Pablo Muriel πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 322 KB πŸ‘ 1 views

The aim of this work was to study if colchicine protects against CCI4 -induced changes in hepatic biochemical parameters by reducing cytochrome P-450, by comparing the effects of colchicine and SKF 525-A, a wellknown inhibitor of cytochrome P-450. Our results show that both drugs reduced the cytochr