Daily granulocyte and monocyte adsorptive apheresis in patients with active ulcerative colitis: a prospective safety and feasibility study
โ Scribed by Takayuki Yamamoto; Satoru Umegae; Koichi Matsumoto
- Publisher
- Springer Japan
- Year
- 2011
- Tongue
- English
- Weight
- 217 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0944-1174
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## Abstract Granulocyte and monocyte adsorption apheresis (GCAP) is a useful strategy for intractable ulcerative colitis, but its mechanisms of therapy is not fully explained. Previously, depleting activated granulocytes and monocytes (GMs) and modifying product of proinflammatory cytokines had bee
## Abstract **Background**: Leukocytapheresis (LCAP) is used as an adjunct therapy for patients with active ulcerative colitis (UC). Although, LCAP is routinely performed at 3,000 mL per session, we were interested to see that if this can be replaced with bodyweight (BW) adjusted volume. **Methods*