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Daily granulocyte and monocyte adsorptive apheresis in patients with active ulcerative colitis: a prospective safety and feasibility study

โœ Scribed by Takayuki Yamamoto; Satoru Umegae; Koichi Matsumoto


Publisher
Springer Japan
Year
2011
Tongue
English
Weight
217 KB
Volume
46
Category
Article
ISSN
0944-1174

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## Abstract Granulocyte and monocyte adsorption apheresis (GCAP) is a useful strategy for intractable ulcerative colitis, but its mechanisms of therapy is not fully explained. Previously, depleting activated granulocytes and monocytes (GMs) and modifying product of proinflammatory cytokines had bee

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## Abstract **Background**: Leukocytapheresis (LCAP) is used as an adjunct therapy for patients with active ulcerative colitis (UC). Although, LCAP is routinely performed at 3,000 mL per session, we were interested to see that if this can be replaced with bodyweight (BW) adjusted volume. **Methods*