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Daily fluctuation of levels of circulating cathodic antigen in urine of children infected with Schistosoma mansoni in Brazil

✍ Scribed by J. Disch; M.M.A. Garcia; G.W. Krijger; M.N. Amorim; N. Katz; A.M. Deelder; B. Gryseels; A. Rabello

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
491 KB
Volume
91
Category
Article
ISSN
0035-9203

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✦ Synopsis

The fluctuation of circulating cathodic antigen (CCA) levels in urine was studied in 69 Brazilian school-children infected with Schistosoma mansoni and compared to egg counts. Faeces and urine samples were simultaneously collected at 7 times during a period of 2 weeks. CCA was determined by enzyme-linked immunosorbent assay and could be detected in 96% of the urine samples; the individual mean CCA level ranged from 609 to 350,700 pg/mL. 90% of the faecal samples contained S. mansoni eggs and the individual mean egg output ranged from 9 to 5510 eggs/g. The Spearman rank correlation coefficient between these individual means was 0.69. Kendall's coefficient of concordance (W) was 0.88 for CCA levels and 0.80 for egg counts.

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