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D2 Receptors May Modulate the Function of the Striatal Transporter for Dopamine: Kinetic Evidence from Studies In Vitro and In Vivo

✍ Scribed by Susan M. Meiergerd; Terrell Ann Patterson; James O. Schenk

Book ID
111177719
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
420 KB
Volume
61
Category
Article
ISSN
0022-3042

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebs‐HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am