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D104N polymorphism in endostatin, an angiogenesis inhibitor, in acute and chronic myeloid leukaemia

✍ Scribed by Helvia Nascimento; Gustavo J. Lourenço; Manoela M. Ortega; Gabriela G. Yamaguti; Fernando F. Costa; Carmen S.P. Lima


Book ID
104040284
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
61 KB
Volume
31
Category
Article
ISSN
0145-2126

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Polymorphism in endostatin, an angiogene
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## Abstract Endostatin inhibits endothelial cell proliferation and migration, prerequisites of angiogenesis. A functional missense mutation (__D104N__) in endostatin was associated with an increased prostate cancer risk in a small study. We undertook a larger, prospective study within the Physician