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D004 Pharmacological blockade of angiotensin II type 2 receptor inhibits tumor growth decreasing cell proliferation and tumor vascularization

✍ Scribed by N. Clere; I. Corre; S. Faure; A.-L. Guihot; E. Vessieres; M. Chalopin; A. Morel; O. Coqueret; L. Hein; Y. Delneste; F. Paris; D. Henrion

Book ID
119637894
Publisher
Elsevier
Year
2009
Tongue
English
Weight
64 KB
Volume
102
Category
Article
ISSN
1875-2136

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Deficiency or blockade of angiotensin II
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✍ Nicolas Clere; Isabelle Corre; SΓ©bastien Faure; Anne-Laure Guihot; Emilie VessiΓ¨ πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 811 KB

## Abstract Despite significant expression level in cancer cells, the role of the angiotensin II Type 2 receptor (AT2R) in cancer progression remains poorly understood. We aimed to investigate the involvement of AT2R in tumorigenesis, hypothesizing a role in tumor cell proliferation and/or tumor an