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d-ribofuranosyl azides. A direct conversion of 1-O-acyl-2,3-O-isopropylidene-d-ribofuranose into d-ribofuranosyl azides

✍ Scribed by Marshall W. Logue; Byung Hee Han


Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
573 KB
Volume
121
Category
Article
ISSN
0008-6215

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An improved synthesis ' of 2,3,5-tri-O-benzoyl-/3-o-ribofuranosyl azide (3) involves the reaction of trimethylsilyl azide in the presence of a Lewis acid with l-0-acetyl-2,3J-tri-O-benzoyl-@-o-ribofuranose 2-4 (1) rather than the action of sodium azide upon the corresponding halide 5. Titanium tetra